The Offensive Movie Clich That Wont Die Essay Example | Topics and Well Written Essays - 750 words

The Offensive Movie Clich That Wont Die - Essay Example Zollar argues that the word â€Å"negro† has been employed differently during the past four decades. It began falling out of fashion 4 decades ago and this may explain why it is apparently devastating. It is a word that was employed to comfort the white and militantly to oppositional the black race. I enquired for both dignity and autonomy without incorporating the more step for the assertion of its existence with or lack of approval of the white American. For example, in the movie called The â€Å"Green Mile,† the power of the character is used to benefit the whites. It may be relatively difficult to comprehend how words such as â€Å"Negro† changed with time since it is usually perceived to be a racist word. Furthermore, the word is offensive as it describes a race and the race in question has been not only striving but also improving with years. The word should not be used due to the fact that it was used to refer to the blacks during the oppressive eras. To elaborate further, president Obama’s election into the highest office or echelon of powers in the US has perhaps created a precedent for a new era. However, controversies should not emanate from this aspect between the blacks and whites especially on race. Zollar’s argument and conviction on racial tension across the globe is relatively impressive. He argues that everything encompasses competition in the world thus the competition concerning the races is not bad. He asserts that the whites are for the success of the blacks and in return aid them.

Protecting our Environment Essay Example | Topics and Well Written Essays - 2250 words

Protecting our Environment - Essay Example Global warming and climate changes are the major outcomes of injudicious human activities. It is believed that sustainment of life in this world may become extremely difficult in near future itself if effective measures were not taken to counter environmental problems. Even though the size of the earth remains the same, global population is growing at alarming rates so that it may become extremely difficult for our earth to accommodate or cater the needs of all the people. As each individual contributes heavily to environmental problems, growth of population means growth of environmental problems also. In other words, population growth is directly proportional to environmental problems. As the world population grows, so does hazardous waste, toxic materials polluting our environment and affecting our eco-system. There should be a coordination effort by governments around the world to control pollution affecting our environment in order for human survival for future generations. Water pollution and preventive measures United States has many federal and state laws that have enacted to protect our water system and help regulate the amount of pollutants that affects our water. However, the implementation of these laws are not much effective so that American water sources are getting polluted more and more as time goes on. For example, Colorado River seems to be one of the major victims of environmental pollution in western American region. More than 30 million people use Colorado River as their major drinking water source. However, Colorado River is dying gradually because of environmental problems. â€Å"If climate change results in a 10 percent reduction in the Colorado River's average stream flow as some recent studies predict, the chances of fully depleting reservoir storage will exceed 25 percent by 2057, according to the study† (Future Of Western U.S. Water Supply Threatened By Climate Change, 2010) Irrigation projects are helping agricultural farming in America. However, water drained o ut of the agricultural lands may contain toxic ingredients because of the increased usages of fertilizers, chemicals and pesticides to improve the agricultural yields. Selenium seems to be the major harmful chemical content in irrigated water drained out of the agricultural lands. â€Å"When selenium uptake is too high health effects will be likely to come about. The health effects of various forms of selenium can vary from brittle hair and deformed nails, to rashes, heat, swelling of the skin and severe pains† (Selenium – Se, 2009). The Environmental Protection Agency, have supported and helped enforcement of water laws in our country and have introduced many laws concerning safe drinking water. The Clean Water Act (CWA) establishes the basic structure for regulating discharges of pollutants into the waters of the United States and regulating quality standards for surface waters. The basis of the CWA was enacted in 1948 and was called the Federal Water Pollution Contr ol Act, but the Act was significantly reorganized and expanded in 1972. "Clean Water Act" became the Act's common name with amendments in 1977. Under the CWA, EPA has implemented pollution control programs such as setting wastewater standards for industry. CWA act was formulated for the purpose of preventing all types of

HR Department Is Playing A More Significant Role Commerce Essay

HR Department Is Playing A More Significant Role Commerce Essay It is said that the HR department is playing a more significant role in organizational strategic planning processes today than it did 20 years ago, how do you explain this? In a company, what difficulties would an HRM executive face in assessing and then communicating to other department heads, the contribution of his or her area to the company profit margin? It is said that the HR department is playing a more significant role in organization strategic planning process today than it did 20 years ago because of these reasons as following: First, today environment business have been changing, companies have reinforced by global competition, technical changing, opportunities difficulty, global employment. By thus, human resource management takes more challenge, classical human management likes order, force and consider employee as other tools that conception is not appreciated. Human resources management is toward to promote and develop human ability accordance with development of organization. Second, today strategy business cannot separate human resource strategy, human resources management supports other departments get their objectives. By thus, roles of human resources department have been changing from it did. It has to invest in human resource for long term, coordinate closely with function departments, human resource appreciation is basement to promote and develop. However, in a company an HRM executive often face in assessing and then communicating to other department heads relevant to salary, reward, promotion, and discipline. Therefore, human resource executive should be professional knowledge about human resource management, building a good communicate with employee, and becomes a bridge between employee and owner to satisfy their objectives. In brief, human resources management connects closely with all activities of organization and it is become a part of strategy management. Question II: Historically, HRM activities and tools were developed and implemented by a department or functional unit. Today, however, operating managers are in the forefront in applying and modifying HRM tools and activities. Why has this shift in application occurred? How is the work of operating managers similar to that of physicians who must conduct a diagnosis before treating a patient? Answer: Historically, human resource management activities and tools were developed and implemented by a department or functional unit. Recently, roles of human resource management have been changing from administration to embedded qualify performance. Strategy of human resource management focuses and integrates into organization strategy. By thus, human resource management is in the forefront of overall strategy organization. Individuals in organization should have responsibilities with all issues of human resource management. Its activities is not limited in labor arrangement, operation manager should take participant into activities of human resources department to ensure that human resources is used most efficient accordance with organization objectives. Human resources management modern uses ARDM model, it is method for operation managers appreciate effective elements to human resource. The ARDM model includes four steps such as diagnosis, prescription, implementation, and evaluation. Similar with a doctor have to define what is reason lead to illness, operation manager have to define status job performance in connection with internal and external elements of ARDM, then they issue prescription, it is activities and remedy to deal with illness status. After that, doctor has to re-test, follow-up examination, operation manager also should re-appreciate influences of prescription. Question III: Sexual harassment is often found in our society. How does EEOC explain sexual harassment? What can managers do to minimize their chance of litigation and being found negligent with regard to sexual harassment? Answer: Sexual harassment is considered a type of sex discrimination provided by EEO of United States. There are two type of sexual harassment, which are quid pro quo and hostile work environment. Quid pro quo is the exchange of sexual favors for job benefits such as increase salary, promotion, or other benefits. Meanwhile, hostile work environment is creation of an offensive working environment. In order to minimize chance of litigation and being found negligent with regard to sexual harassment, organization should apply measurements to eliminate sexual harassment. Companies have to setting up a policy to prevent from sexual harassment, and inform to all staffs to element absolutely. Besides that, companies have to investigate carefully and strictly to deal with accuse of sexual harassment. Difference from the U.S, Vietnamese impacted on oriental and traditional culture, so people are not opened and very shy to talk about sexual especially women. Therefore, in Vietnam organization, sexual harassment issues are difficult to exposing. However, sexual harassment likes as artesian waters flows in all companies and become pervasive. This actual motivates managers who focus on educating and establishing the rules comprises disciplined for acts of sexual harassment. In my opinion, starting with Vietnamese experience is à ¢Ã¢â€š ¬Ã…“prevention is better than againstà ¢Ã¢â€š ¬Ã‚ , I think that every individual should try your best to protection yourself from sexual harassment in the workplace. Question IV: Where would you place yourself on each of the five work-related cultural dimensions identified by Hofstede (e.g., high on individualism)? Why? Explain the Sullivan Principles? How have these principles helped organizations understand the ethical issues they face when conducting business in foreign cultures? Answer: According to Hefstede, there are five aspects culture to evaluation a culture, and compare among different cultures, which includes such as individualism versus collectivism, power distance, avoidance of uncertainty, masculinity, and long term versus short term orientation. These examinations can list out knowledge about various cultures, this study is very useful to working in multi-national company. The result of research about dimensions culture of Vietnam and compare with several cultures is show as following: Country Power distance Individual versus collectivism Masculinity Avoidance of uncertainty Long-term versus short term orientation Vietnam 70 20 40 30 80 China 80 20 66 30 118 Japan 54 46 95 92 80 The U.S 40 91 62 46 29 Cultural nations are different from dependence on natural culture, education, and system of law. Sullivan listed out six principles to deal with cultural differences in multi cultural working environment. Despite, these principles give in Appartheid period but it can apply in many countries because its aims toward to person, services for human and human rights. These principles is similar with a guidance for companies to protect human rights, create an equal opportunities, ensure a good working condition, good heath, increase standard of living and so on. Question V: As a current (or future) manager, how will you communicate the requirements of an entry-level customer service representative to a candidate who just arrived at your office for an interview? Will you describe the job in terms of competencies? Knowledge, skills, or abilities? Explain your answer. Answer: As a current manager, when a candidate arrived at my office for an interview, I will indicate to applicant my organization requirement of an entry-level customer service representative. These requirements are detailed as job description and specifications which was carefully studied by candidates. Therefore, interviewer just only talks to interviewee about advance requirement for future requirement of organization, accompany with firm strategy. Today, candidates often consider about ability to development and promotion, it is important element to attract candidate joining to our organization. By thus, this information is very useful and helps candidates imagine about their career, prepare knowledge, change study to accordance with firm strategy, changing business environment. By thus, candidates who are distance from traditional requirement need satisfy KSAO for entry-level customer service representative responsibility. However, organizations often prefer candidates who can competencies for several assignment even other position. Manager should give program in order to supporting of staffs implement competencies, throughout they can become flexibility. As a result, human arrangement becomes more elastic. For example, an entry-level customer service representative is not only welcome customer in the first step but also he or she can move to other step to continuing with customer requirement Question VI: Recently some companies began to use temporary employees? Do you know why? Assume your company wants you to make a recruitment advertising for hiring temporary employees, what guidelines will you follow to make sure that recruitment advertising does not violate equal employment laws? Answer: During twenty years ago, using temporary is become pervasive trend. There are several reasons to explaining for this trend as follow: Business competition is getting more challenge, technical development influences on doing business, which leads that companies always face re-organized, by thus, human resource management have to enthusiastic to match on the challenges, environment changing very fast. Beside on building a competencies human resource, organizations often use temporary employee to deal with shortage of human resources, and this method can find employee quickly. Moreover, there are server advantages when company can use temporary such as low expenditures, reducing social benefits, do not training, can find fit candidates in short time, and using temporary is not effect to re-organized. In Vietnam, using temporary is more common in manufacture, production than others, and temporary are often with low qualification, and worker mainly. There is a notice that organization should study carefully law, stipulation or regulations especially EEO law before building an advertisement for recruiting temporary employee. In order to braking out law or stipulation, advertisement has to execute several principles such as avoiding preference or priority for any race, sexual, religions, nation, skin color and so on

The Lord of the Rings Essay -- essays research papers

The One Ring to rule them all   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Thought-paper on J. R.R. Tolkien’s The Lord of the Rings By Francis Byron P. Abao 97-06526 English 146 Inst. Emil Flores Department of English and Comparative Literature University of the Philippines Diliman, Quezon City. Submitted on October 14, 2002. The One Ring to rule them all   Ã‚  Ã‚  Ã‚  Ã‚  The Lord of the Rings is a three part epic fantasy by J.R.R. Tolkien about the struggle to destroy the One Ring of Power. Published in 1954, the work remains as relevant today as ever, when the question of power and its consequences is concerned. In fact, the work reached the height of its influence in the antiwar protests of the 1960s, where it was a main source of inspiration for activists. Part of the reason for its enduring appeal may be that it resists any one to one correspondence of symbolism and meaning. And so, people are drawn into endless debate and speculation as to what Tolkien ‘really’ meant by his story. If Tolkien had cast his work into a form that was more easily interpreted, if he had been more dogmatic and called it ‘The Use and Misuse of Power,’ for example, he would perhaps have been less effective and influential. This is because dogmas easily attract fanatics and people who want ready made answers, but disenchant th ose who are inclined to a more liberal, questioning approach toward life. Tolkien’s work, fortunately, was not designed to be anything as overtly political as Marx’s ‘Communist Manifesto.’ It is a work of fantasy-literature, a combination which makes it hard for conservatives of the literary or political sphere to consider it seriously as purely a work of literature or political dogma. Nonetheless, it undoubtedly has something to say about the connection between politics, morality, and it says this in an imaginative medium: fantasy.   Ã‚  Ã‚  Ã‚  Ã‚  Despite the fact that we may never know what Tolkien meant, we can always ask(and answer, to an extent) what Tolkien means for me---as a reader, as an individual. If the work endures to this day, it must be because it concerns questions that many people have found to be relevant and enduring.   Ã‚  Ã‚  Ã‚  Ã‚  One such question for me is the question of the use of power and it... ...or as long and as well as we can, to preserve and care for our place in the world and our relationships to others in it. And even if we fail, we do not if our attempt has been in vain, or, if it is part of some greater plan of some Higher Power who has our best interests at heart. The attempt itself is heroic.   Ã‚  Ã‚  Ã‚  Ã‚  But I think that Tolkien defined the best of what it means to be human in his work: that is, when faced with a crisis which seems beyond our means of coping, we choose hope over despair; trust over doubt; and faith over cynicism. â€Å"I don’t suppose we shall see them again, do you Sam? Frodo asks at the breaking of the Fellowship. â€Å"Yet we may, Mr. Frodo. We may.†Sam replies. (Tolkien 526). References: 1.  Ã‚  Ã‚  Ã‚  Ã‚  Tolkien, J(ohn) R(onald) R(euel). The Lord of the Rings: The Fellowship of the Ring. U.S.: Ballantine Books, 1965. 87,93,526. 2.  Ã‚  Ã‚  Ã‚  Ã‚  Asimov, Isaac. â€Å"The Ring of Evil† The QPB Companion to the Lord of the Rings New York: Houghton Mifflin Company, 2001. 94. 3. Day, David. Tolkien’s Ring.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   London: Harper Collins Publishers, 1994. 51.

Effects OF Watching Too Much Television Essay

Watching television is an experience shared by most adults and children. But the problem is that watching television for long periods of time has many bad effects. The purpose of this essay is to persuade the reader that people shouldn’t watch too much television. The first reason why people shouldn’t watch television for long periods of time is that it makes people waste time that could be used in more beneficial activities. This wasted time could be used to make useful activities like exercising, interacting with friends and family, and reading. The second reason is that the content of many television programs is not educational. Movies and series nowadays have lots of violence, sex, and drugs scenes. This tendency has very dangerous impact on children because they grow up with the idea of a world where problems can only be solved with money and violence and where wars are inevitable. The third reason is that watching television increases the audience desire in eating which causes obesity. Because they always sit in front of the screen and they forget to do physical exercises. After the invention of television on 1923, it is found that the rate of obesity, heart attacks, and eyesight problems is increasing. According to a new study, watching television too much increases the risk of dying at an earlier age, especially from heart disease. This research says that every hour you spend in front of the television increases the risk of dying from heart disease by 18 percent and increases the overall risk of death by 11 percent. However this doesn’t mean that we should ban television, but if we are going to watch it, we should do it with moderation.

Case Study Wal-Mart Essay

Evaluate the general environment of Wal-Mart using the framework in Chapter 2. What are the key opportunities and threats facing Wal-Mart? (This is the â€Å"OT† of a SWOT analysis)Wal-Mart’s builds its stores in towns with a population size of 5000-25,000 people. Wal-Mart has recently started to tap into the more populated city suburbs by building smaller less obtrusive stores in those regions. Wal-Mart targets every age group from infants to senior citizens. Wal-Mart’s geographically places it’s stores in rural less populated areas with very few employment opportunities. Wal-Mart tries to attract all income levels by selling brand name items along with generic brand items. Wal-Mart approaches its global market by evaluating market potential based on economic and political risk, growth potential, and availability of real estate for development. In countries that had became saturated Wal-Mart used acquisitions to acquire ownership. In markets that were not saturated and land was easily accessible Wal-Mart used organic growth. The technology that Wal-Mart uses to run their business is unmatched. They have a network of satellites that can track a person purchase and automatically refurbish those items from suppliers without any human intervention. Wal-Mart maximizes efficiency by using effective technology to gain a competitive advantage. Wal-Mart has grown into a global empire and has become the world largest private employer and the number one retailer in the world. Despite all of this success Wal-Mart still has a huge opportunity to grow. Wal-Mart continues to adapt to the ever-changing economy by remodeling their store and by placing the customer as their number one priority. Wal-Mart took advantage of its rural locations early on and gained a significant competitive advantage, now Wal-Mart is taking on the urban environment by placing stores in the outskirts of major metropolitan areas. At first local residents rejected the idea of having a Wal-Mart in their neighborhood for fear it would drive down property value and unwanted individuals to their suburbanite neighborhood. Wal-Mart quickly resolved this problem by changing the format and size of their stores located in these regions. The only threats to Wal-Mart faces are mostly from within (eg..) lawsuits employee disputes and the threat to become unionized. Use Porter’s Five Forces Model to analyze the global retailing industry. Given this analysis, is the industry attractive or unattractive? Support  your decision. Wal-Mart is a huge threat to new entrants. Wal-Mart has created huge barriers to new entries by offering one stop shopping. Wal-Mart’s Super Centers offer everything from prepared meals to sports gear. Grocery chains have taken a huge hit because of this, even Kmart is feeling the heat, there stock hit rock bottom in 2004. The discount clothing and apparels have also taken a bite from this retail giant. Wal-Mart has produced a very proficient economy of scale from incremental improvements that they have acquired since becoming so large. Manufactures scramble to try and keep up with the huge demand that Wal-Mart places on its suppliers, this further reduces the prices of goods and services for their customers. Small-scale entries are nearly impossible in a region where Wal-Mart is located. Large-scale entries face the retaliation factor when trying to tap into Wal-Mart’s market because suppliers are forced to do things the Wal-Mart way. Wal-Mart has successfully customized many of their products and forced manufactures have been forced to produce the Wal-Mart brand. Wal-Mart has taken total control of the bargaining power of suppliers. Wal-Mart has a small group of buyers based in Bentonville Arkansas that’s in charge of managing the purchasing of all retail stores. Wal-Mart is responsible for selling 35% of all pet food, 24% of all toothpaste, the largest volume of jewelry, groceries, DVDs, CDs, toys, guns, diapers, sporting goods, bedding, and numerous other things. This has put the retail giant in a very favorable negotiating position with suppliers. Wal-Mart has generated a huge market of loyal buyers by supplying them with the lowest possible prices for quality products. With Wal-Mart having such a huge share of the market and good prices there is no need for buyers to seek deals elsewhere. Wal-Mart has proven to be a huge threat of substitute products in several industries for example the jewelry industry, Wal-Mart has become one of the leading jewelry dealers in the North America. Wal-Mart has also created its own brand name for several of its items that have been so successful that manufactures are forced to produce products bearing the Wal-Mart brand. Wal-Mart competitors have to be very calculated with their responses because Wal-Mart is so large it can really drive a business under ground (Kmart). What is Wal-Mart’s business-level strategy? Is the strategy appropriate to offset the forces in the industry? Do you recommend any changes? If not, support your decision why you would not recommend any changes. Wal-Mart uses Integrated Lost Leadership/Differentiation Strategy. Wal-Mart has offset the forces in the industry by creating the most efficient supply chain in the industry. Efficient production has allowed Wal-Mart to keep cost low and pass own saving to its customers. Wal-Mart has successfully used Integrated Cost Leadership/Differentiation Strategy by setting the pace in new technology and adapting quickly to new technologies in their external environment. Concentration on the needs of its core customers (discount retailers), Wal-Mart has created a friendly family environment that’s economically smart and beneficial to its patrons. Flexibility is one of Wal-Mart’s strongest assets, which allows them to complete primary and support activities in ways that allow them to produce somewhat differentiated products at a low cost. I would not personally recommend any changes to this strategy because it has made Wal-Mart the worlds largest retailer. What is your evaluation of the leadership at Wal-Mart?Wal-Mart has become the most successful business in the world through its un-yielding leadership. Mr. Walton has laid the foundation for success for years to come. The leaders at Wal-Mart focus on providing the customer with the highest possible quality at the lowest possible cost. They have redefined the retail industry with their cutting edge technology and flexibility that is un-matched by any competitor. The fact that upper management travel in economy class shows a lot about the character within the organization. The leadership at Wal-Mart has made the world we live in much smaller through economic availability and convenience. The leaders at Wal-Mart are a true example of profit through customer satisfaction. Works Cited Hitt, M., Ireland, R., & Hoskisson, R. (2007), Strategic Management, Competitiveness andGlobalization: Concepts and Cases. 7th ed. Mason: Thomson South-Western(August 21, 2006). Global Labor Strategies: Wal-Mart: The Homefront. RetrievedSeptember 18, 2007,

Cognitive Dissonance and the movie 2001 essays

Cognitive Dissonance and the movie 2001 essays The argument that the paper states is that a persons wants and desires influence more than just behavior. They influence his/her thinking and even his/her power of perception. The most important point made is that when a person is confronted by ideas or facts that are against their pre-existing notions and ideas, what results is cognitive dissonance. Cognitive dissonance is referred to as a sort of static in the human psyche. This static caused by cognitive dissonance has the power to distort or even block perception. When disturbing information creates cognitive dissonance, the static discredits the information, so that a person does not feel compelled to cope with it, even if it is true. Cognitive dissonance is a very powerful self-preservation mechanism that can completely override the human desire for truth. The movie 2001 illustrates the points the author is trying to make. The fact that the geometric slab is kept secret is an example of the potential for cognitive dissonance. The government feared that if the Earths inhabitants learned of it without adequate preparation and conditioning, widespread culture shock and social disorientation would inevitably ensue. This disturbing information would have created a cognitive dissonance with the earths inhabitants; the people would simply discredit the evidence so that they would not have to cope with the far-reaching effects. I agree with the argument made about cognitive dissonance and the illustration with the movie. I dont really believe the producers of the film 2001 intentionally set out to make a film tackling the psychological issue of cognitive dissonance, but somehow stumbled upon it. ...

Free Essays on Aggression As A Concept

Aggression is a social behavior that differs throughout cultures and society. Aggression is also a trend that occurs in nature’s wildlife. Some animals are more aggressive than others. For example, lions can and will attack almost any other animal for its prey. This is very different behavior from a giraffe that can barely defend itself while feeding on a nearby tree. Some societies seem to have more aggressive behavior than others. Germany, when under the influence of Hitler, had a very high death rate among its Jewish population, which devastated many families. Aggression can also be a biological trend through a family’s genes and DNA. Researchers have tried to link aggression to heredity and hormones. Many structures in the brain have been found to be very significant in studying aggression within families. A high level of the hormone, testosterone, has also been linked to aggressive behavior. These are very interesting aspects of aggression, but this essa y will mainly focus on aggression as a product of social learning. The social learning theory explains that aggression is likely to be learned by watching others who have an aggressive nature in their actions, which is very dangerous. Violence is usually a result when dealing with aggression among society. In Sdorow’s Psychology textbook, he states that researchers have found women to be more aggressive after watching their parents act aggressively. A study conducted by Albert Bandura showed that children acted aggressively towards a â€Å"Bobo doll† after seeing an adult hitting the doll several times. The behaviors towards the doll were very different than those of children who did not observe any aggression towards Bobo. Children are also more likely to show aggression towards other children after watching a violent show on television. Many cultures and countries other than the United States show aggression in their society. Rome used to hold gladiator e... Free Essays on Aggression As A Concept Free Essays on Aggression As A Concept Aggression is a social behavior that differs throughout cultures and society. Aggression is also a trend that occurs in nature’s wildlife. Some animals are more aggressive than others. For example, lions can and will attack almost any other animal for its prey. This is very different behavior from a giraffe that can barely defend itself while feeding on a nearby tree. Some societies seem to have more aggressive behavior than others. Germany, when under the influence of Hitler, had a very high death rate among its Jewish population, which devastated many families. Aggression can also be a biological trend through a family’s genes and DNA. Researchers have tried to link aggression to heredity and hormones. Many structures in the brain have been found to be very significant in studying aggression within families. A high level of the hormone, testosterone, has also been linked to aggressive behavior. These are very interesting aspects of aggression, but this essa y will mainly focus on aggression as a product of social learning. The social learning theory explains that aggression is likely to be learned by watching others who have an aggressive nature in their actions, which is very dangerous. Violence is usually a result when dealing with aggression among society. In Sdorow’s Psychology textbook, he states that researchers have found women to be more aggressive after watching their parents act aggressively. A study conducted by Albert Bandura showed that children acted aggressively towards a â€Å"Bobo doll† after seeing an adult hitting the doll several times. The behaviors towards the doll were very different than those of children who did not observe any aggression towards Bobo. Children are also more likely to show aggression towards other children after watching a violent show on television. Many cultures and countries other than the United States show aggression in their society. Rome used to hold gladiator e...

Carbon Tax Conclusion

My final argument will be based on the effectiveness of this tax: The tax will have no significant impact on greenhouse gas emissions. It has been claimed that an Australian carbon tax will have no significant impact on the level of greenhouse gases in the earths atmosphere. This claim has been made on two bases. Firstly that it is unlikely to succeed in significantly reducing Australian greenhouse gas emissions and secondly, that even if these emissions were to stop completely this would have no useful effect on world greenhouse gas emission rates. Critics of a carbon tax for Australia argue that it will damage our economy without reducing climate change. The independent think tank, the Institute of Public Affairs (IPA) has stated that the proposed tax, although burdensome and damaging is not sufficiently large to force reinvestment in different forms of power generation. In a media released issued on March 2, 2011 and published in The Age, the IPA stated, The price itself, while severely harming the carbon-intensive, coal-based generators, would not force their premature departure from supply, which would be necessary to leave a gap for new gas generators. The IPA Review in September 2008 included the following response to Kevin Rudds proposed emissions trading scheme, Australia contributes 1. 1 per cent of total global greenhouse gas emissions. Our contribution is dwarfed by big emitters like the United States which contributes nearly 21 per cent, China which contributes 17 per cent, and Russia which contributes just over 5 per cent. All in all, there is no positive outcome for this tax, yes it is true that it reduces greenhouse gases, but things cannot always be solved with money. If we, as the Australian people want to make our environment cleaner, we should not just pay up to the government to clean our environment, we live in it, so we must put in some effort to prevent this ongoing issue. Thank you.

Revolution in russia 1917 Essay Example | Topics and Well Written Essays - 4250 words

Revolution in russia 1917 - Essay Example Moreover, as per the historical perspective, the act of revolution is regarded as a movement that is often highly violent undertaken to overthrow or make significant changes in the old regime and completely change the fundamental scenario of society for betterment. In the 18th century, the French Revolution evidently refashioned the entire society with the aim to make people believe that transformation can be achievable through rebel and violence. Likewise, a significant example of revolution of the 20th century was the Russian Revolution of 1917, which was led by Vladimir Lenin (Neitzel 1-2). Correspondingly, the paper intends to highlight the aspects of Russian revolution 1917 and its changing dimensions. Besides, in this regard, the paper explores the key reasons behind the introduction of revolution in the Russian economy. The paper will also demonstrate the relationship between government and the inhabitants during the revolution. The paper will also recognize the key aspects in terms of the impact of the revolution over the Russian economy through identifying the series of activities involved. In this respect, the essay will also explore the prior cause of Russian revolution. Since, 1533 Russia was under the governance of tsars, who were regarded as second largest in terms of their courage and power in the global scenario. In the 19th century and the early 20th century, students, workers, members and peasants introduced movements to overthrow the government. Moreover, the 1825 revolt against Nicolas I as well as the 1905 revolution was the two unsuccessful movements that aimed at establishing constitutional monarchy in the nation (Stobaugh 222-223). Moreover, the main reasons of the dilemma in the government regime stemmed from incompatible transformation of the nation into a modern economy. On the other hand, industrial society was in the autocratic mode before the revolution. Besides, the fall of Russian

Emotional intelligece Research Paper Example | Topics and Well Written Essays - 500 words

Emotional intelligece - Research Paper Example In order to attain high level of emotional intelligence, one is required to firstly, recognize their emotions. Managing one’s emotions help in avoiding conflicts and embarrassing other people. For example, when a person says something wrong in a meeting, you only need to correct them after the meeting, but not when the meeting is on session. Secondly, one needs to manage their emotions. This helps you communicate effectively with colleagues in a clear manner without creating any misunderstanding. Thirdly, you need to recognize other people emotions. This way, you are able to avoid any conflicts that could have occurred and it helps in maintaining personal and group peace. Lastly, one needs to effectively respond to others emotions. By doing so, you make other experience a sense of belonging in any company. Also, in order to improve emotional intelligence, one needs to be empathetic, have self-regulation, motivate others and be aware of himself or herself.   Working with lead ers of different emotional intelligence from that of his or her employees would be a challenge. However, this is achievable through acquiring skills that will improve the relationship. Such skills include understanding and observing the way they react to other people, understanding their environment, performing personal evaluation, cross examining the way they react to stressing conditions, being responsible of their actions and understanding the way their actions affect others.

B2C to B2b Marketing Paper Essay Example | Topics and Well Written Essays - 1000 words

B2C to B2b Marketing Paper - Essay Example Traditionally, businesses begin as B2C but as they expand and look for new markets develop a B2B operations. However, this model of development has significantly changed because of advances in technology. Though B2C and B2B's characteristics essentially remain the same, they have already exceeded their basic definitions. B2C refers to businesses dealing directly with consumers. The action of purchase is for the purpose of personal consumption. It is not to imply that the customer or consumer has to procure the product or service directly from the manufacture or service provider, B2C can take the form of a person buying a product from a store or person availing of a free spa treatment with a gift certificate or voucher. B2B in contrast refers to businesses engaging the service or procuring products for their own operations and not for consumption. An example of B2B would be a bakery buying flour to produce its breads. The criteria defining whether the interaction is B2B or B2C is consumption (Koetler, 1998). The objective in a B2C model is to promote or market a site is to be able communicate on a personal level. Each consumer will have different motivations and these motivations may vary greatly considering individual perception, socio-cultural background (both demographics and psychographics), and experience. These elements define the customers' needs which initiate the buying process. The following figure is an example of a depiction of what influences consumer behavior: Therefore, sites that wish to appeal to consumers have to focus on the characteristics of customers and to consider the decision process of these customers which characterizes the type of person that consumer is. In contrast, B2B customers' motivations or preferences are generally based on quantitative pre-defined needs or criteria. B2B transactions generally arise from the following: 1. Raw material or industrial supplies or services are needed to produce an end product to be sold in the open market 2. Raw material or industrial supplies or services are needed as components of processing a product 3. Products or services are bought form an original manufacturer for resale 4. Products or services are bought from s non-original manufacturer for the purpose of distribution 5. Products or services are bought as a complete system or "turnkey" operation. Figure 2 illustrates the buying process that characterizes the undertaking of B2Bs. It is not required that all of these stages are passed through in each B2B transaction. At this level, buyers are limited by the people and other factors that affect the company. This then highlights the influence organizational culture plays in the buying process. Therefore, in marketing a site on the B2B model, the marketer must consider not just that direct need but also the main use of the product, its users and even the tendencies or preferences of senior executives and others who have bearing on company policies (Johansson, 2001). Differentiating Approaches in B2C and B2B Table 1 summarizes the differences between B2B marketing and B2C marketing. Marketing

Meeting Essay Example | Topics and Well Written Essays - 1000 words

Meeting - Essay Example Conduct Meetings, what do you do if one of the people in the meeting started to talk about things which are not related to the purpose of the meeting? The â€Å"tangentially inclined individuals† are people who take off on unrelated subjects, thereby derailing the conversation and interfering with the pace of the meeting. This may happen if meeting goals/outcomes are not clearly defined, or if the level of detail or the meeting roles are not understood. To handle this scenario, the facilitator must stop and clarify the desired outcome for this particular topic. If possible, he/she must help the group agree on level of detail to discuss before the meeting even gets started. He/she can use a parking lot to record issues to be worked outside the meeting. Finally, he/she should make sure that people feel heard. The most appropriate meeting chairperson is somebody who is (1) level-headed, because meetings can get heated up sometimes, so someone who can keep the harmony in the proceeding is vital; (2) objective, because opposing views are inevitable in meetings, so someone who can weigh the pros and cons can keep things in proper perspective; (3) intelligent enough to understand everything that transpires in the meeting; and (4) sensitive to the fact that everyone’s ideas and personality differences are recognized. b.  How will you ensure that the meeting is time efficient and desired outcomes can be achieved efficiently? E.g. what may be an appropriate time limit on each speaker and how will you try to restricting discussion to agenda items? For the meeting to be time-efficient, certain guidelines must be made clear to all attendees, especially on the issue/s to be discussed so as to avoid veering away from what is relevant. Also, limits to the duration that each speaker can talk must be set, i.e., 2 minutes to present his/her main idea/concern, then ask for extension if necessary. c.  Give at least 2 examples of ethical and legal requirements for a public

Administering the questionnaire survey Essay Example | Topics and Well Written Essays - 500 words

Administering the questionnaire survey - Essay Example phical limitations they may put into effect on the surveys and the vast resources needed if such surveys need to be done nationally or internationally. The cost of training interviewers in questioning methods, traveling cost, and interpretation of response is also high. In addition, respondents might feel apprehensive about the ambiguity of their responses when they interact face-to-face interviews. In long interviews, either tiredness or edginess can affect the quality of responses as the interview progresses. Interviewers must be willing to face potentially unlikable and risky situations alone, be able to come up to strangers and need to have the personal skills to conduct an interview. Face-to-face interview can be negatively affected by the noticeable characteristics (gender, race, class) of an interviewer. For example, there might be different responses on questions such as abortion and attitudes to sexual mores if there is gender difference. However, the advantage of face-to-face interview is that the interviewer has got the flexibility of adjusting questions as per the situation, clarify doubts, if any, and ensure that the responses are properly understood by repeating the questions. Moreover, the interviewer can also use non-verbal cues from the respondent. Any embarrassment or stress experienced by the respondent can be felt through frowns, and other body language, unconsciously exhibited by any person. Telephone interviews are interviews that are held over the phone. Telephone interviews involve making telephone contact with selected sample members and asking the questions over the phone. Telephone interview methods allow skilled interviewers to build rapport yet maintain considerable respondent anonymity. The main disadvantage of telephone interview is that the respondent could unilaterally terminate the interview without warning or explanation by hanging up the phone. It requires skilled professionals who could interact with the respondent in a

Starbucks strategy Essay Example | Topics and Well Written Essays - 2000 words

Starbucks strategy - Essay Example Finally or fourth, the business strategy must define the broad terms that will put the business on a secured foothold in its area of business. Each distinct business endeavour must have its own business strategy so that if a business covers several business areas then it must have several business strategies (MacMillan and Tampoe 2000, p. 171). Although there is a tendency for a business strategy to be lengthy, a business strategy document must be short enough so that the document can be read and understood in one sitting (MacMillan and Tampoe 2000, p. 17). The content of business strategy can cover strategic intent, the principal findings of a strategic assessment, the strategic choices that have been made and the supporting rationale, a statement of goals and objectives, and an outline of the strategic initiatives (Macmillan and Tampoe 2000, p. 17). There are several business strategy formulation frameworks that businesses use in their business practice as well as employ in articul ating their business strategy. Based on the preponderance in the literature, it seems that two of the most popular ones are Michael Porter’s Five Forces Strategy Formulation System and the Blue Ocean Strategy Formulation System of W. Chan Kim and Renee Mauborgne. Both approaches have a sizeable following and appear to be a contrast of strategy formulation framework for business. ... 1). Kim and Mauborgne (2005, p. 106) describes the blue ocean strategy as the strategy that seeks a market where there are no competitors known as â€Å"blue oceans†. According to Kim and Mauborgne (2005, p. 106), a blue ocean strategy implies being uncontested in the market, irrelevance of competition, creation and capture of new demand, value for money, and aligning firm attention towards a focus on differentiation and lower costs. The Kim and Mauborgne perspective utilize the analogy of a blue ocean that is calm and without competition that can make the blue ocean very bloody or red. Porter’s Five Forces Analysis and Kim and Mauborgne’s blue ocean strategy do not exhaust the possible variations of available business strategy formulation frameworks but the two business strategy formulation frameworks probably state the spectrum on which the various business strategy formulation frameworks can be found. II. Starbucks through time and today We trace the history o f growth of Starbucks Corporation based on its postings through its official website at www.starbucks.com and official reports that the corporation gave to government agencies. Starbucks Corporation started from a single narrow-front store selling coffee beans in Seattle’s Pike Place Market (Starbucks Corporation 2010a). The corporate name originated from the Moby Dick novel and was intended to evoke the romance of the high seas and the early coffee traders (Starbucks Corporation 2010a). The current Starbucks Chairman, President, and Chief Executive Officer had walked into a Starbucks store in 1981, fell in love with Starbucks coffee, and joined the company a year after. However, in 1983, Howard Schultz travelled to Italy, was exposed to Italian coffee bars, and has been described

Administering the questionnaire survey Essay Example | Topics and Well Written Essays - 500 words

Administering the questionnaire survey - Essay Example phical limitations they may put into effect on the surveys and the vast resources needed if such surveys need to be done nationally or internationally. The cost of training interviewers in questioning methods, traveling cost, and interpretation of response is also high. In addition, respondents might feel apprehensive about the ambiguity of their responses when they interact face-to-face interviews. In long interviews, either tiredness or edginess can affect the quality of responses as the interview progresses. Interviewers must be willing to face potentially unlikable and risky situations alone, be able to come up to strangers and need to have the personal skills to conduct an interview. Face-to-face interview can be negatively affected by the noticeable characteristics (gender, race, class) of an interviewer. For example, there might be different responses on questions such as abortion and attitudes to sexual mores if there is gender difference. However, the advantage of face-to-face interview is that the interviewer has got the flexibility of adjusting questions as per the situation, clarify doubts, if any, and ensure that the responses are properly understood by repeating the questions. Moreover, the interviewer can also use non-verbal cues from the respondent. Any embarrassment or stress experienced by the respondent can be felt through frowns, and other body language, unconsciously exhibited by any person. Telephone interviews are interviews that are held over the phone. Telephone interviews involve making telephone contact with selected sample members and asking the questions over the phone. Telephone interview methods allow skilled interviewers to build rapport yet maintain considerable respondent anonymity. The main disadvantage of telephone interview is that the respondent could unilaterally terminate the interview without warning or explanation by hanging up the phone. It requires skilled professionals who could interact with the respondent in a

Pop Culture Essay Example for Free

Pop Culture Essay Throughout, history popular culture has been a common factor in everyday life. The identity of popular culture is seen through many elements of art. It was derived from artifacts and styles of human expressions developed from the creativity of ordinary people, and circulate among people according to their interests, preferences, and tastes. For example, music, fashion, people, stereotypes, and social rituals all play a role in the development of what is known today as pop culture society. These elements have shape society to behave and think a certain way, all in which are seen to have a more negative impact to the public rather than promote positive influences. Moreover, we will examine three main elements of popular culture that affect the American culture on a day to day basis. â€Å"Stereotypes, social rituals, and arts are all elements of popular culture that have been adopted and appeals to large masses of people, normally the middle class citizens† . Thus, popular culture comes from people; it is not just given to them. This perspective tears away at distinctions typically made between producers and consumers of cultural material. According to Webster stereotypes are oversimplified opinion, prejudiced attitude, or uncritical judgment. For example, â€Å"people develop conceptions about certain groups of people because of what we see on television and use these generalizations in everyday life, such as Gender and where the media portrays ones masculinity and femininity† 2. Stereotypes can be seen with real or imaginary people or objects. For example, real icons such as expensive cars can be portrayed as a person being wealthy with luxury. Imaginary icons are things such as Bat mobiles or spaceships that are seen as a â€Å"warp speeding icon expressing in truly magical ways- faster than light travel, to demonstrate power beyond discovery† 3. Other real or imaginary stereotypes are heroes. For instances, Martin Luther King Jr. is a known for leading many Americans to freedom from slavery and racism. On the hand, Superman is an imaginary hero that saves the world from danger. These stereotypes have shaped America’s beliefs to be based on judgments of their own opinions as opposed to the truth. Social Rituals consist of â€Å"highly patterned symbolic events in which we all participate as a way of marking important passages in our individual lives or in society as a whole† 4. For example, holidays such as Christmas which is only celebrated by some who believe in decorating and exchanging gifts for the birth of Jesus Christ. However, others prefer not to engage in certain holidays or activities. Moreover, rituals integrate with heroes and icons that are built from a base structure of hierarchy. For example, voting is a common social ritual that plays a significant role in many American’s life. After voting, many constituency wear clothing to symbolize their heroic effort or support for the candidate they endorsed. Art is one the largest rooms of pop culture with a vast and diverse amount of subdivisions. Art includes; magazines, movies, television, recordings, comic books and others. Art correlates with all forms of pop culture and its affects with society. For example, books discuss heroes, icons, stereotypes, people, myth, beliefs and values. All of these elements interact with one another and result in moving to another room that leads to other possibly subcategories. Thus, arts are group together based upon shared characteristics which are known to both popular artist and the audience. Pop Culture is a trend that many learn about through film, media, music, people, fashion and others. These trends can sometime have a negative effect on the way society may behave or act to certain situations. For instances, many people use stereotypes to judge others or relate their lives to those individuals. In addition, others use heroes whether they are real or imaginary to compare and contrast their way of living. On the other hand, there are other elements of pop culture that make up these special trends. For example, social rituals is another element that allows people to express themselves based on their belief, things such as holidays, voting, and weddings. Lastly, Art is the element of diversity it relates to all subcategories of pop culture, within these categories all elements interact and form other elements.

Plasmodium Falciparum Life Cycle

Plasmodium Falciparum Life Cycle Malaria is one of the world leading causes of death, especially among people living in sub-Sahara Africa and other tropical regions. Of the five species of the genus Plasmodium, the malaria protozoan parasite, known to infect Man, Plasmodium falciparum is responsible for the most virulent, severe and dangerous form of human malaria. Over the years, chemotherapy has played central role in the strategies towards the eradication of this disease. However, ability of P. falciparum to develop resistance to effective and affordable drugs and to pyrathroids, the active principle of the insecticides treated nets (ITNs) has made constant search for new pharmacotherapy imperative. This review presents an overview of the life cycle of the causative organism (P. falciparum), the efforts at controlling the disease and the molecular and cellular basis of the infection, with special emphasis on molecular chaperones of the heat shock proteins family as critical components of the parasite intra-erythr ocytic development and survival. The motivation for the present work is also presented. 1.1 Introduction Malaria, whose pathogen is transmitted by female Anopheles mosquitoes, is both preventable and curable, but yet still impacting negatively on the health of millions of people and account for high rate of mortality, especially among children in sub-Sahara Africa (Breman, 2001; Greenwood et al., 2008; Hay et al., 2004; Rowe et al., 2006; Snow et al., 2005). Five species of the genus Plasmodium, the protozoan parasites, responsible for malaria infection are known to infect humans. They are P. falciparum, P. vivax, P. malariae, P. ovale and P. knowlesi. It has been proposed that P. ovale consist of two species (Cox-Singh, 2010) and that zoonosis is the medium through which P. knowlesi infect humans (White, 2008). Of these, P. falciparum and P. vivax are numerically most important, with the former responsible for the most virulent, severe and dangerous form of human malaria (Greenwood et al., 2008). The World Health Organization (WHO) 2011 Malaria reports (WHO | World Malaria Report 2011, 2012) estimated a total of 216 million episodes of malaria in 2010 with at least 655 000 deaths, mostly in Africa and among children under the age of 5 years. Malaria was reported to be prevalent in 99 countries with an estimated 3.3 billion people at risk. Though, supports by international donors has led to rapid decrease in malaria mortality, especially among adults in Africa, Murray et al., (2012) contended that the malaria mortality burden may actually be larger than previously estimated and that for the necessary elimination and eradication to be achieved at larger scale, there is an urgent need for more supports. Factors, such as lack ofsanitation, malnutrition, lack or reduced access to medications, poverty and the location of many of the poor countries affected by malaria in the tropical zones, all combined together to create an enabling environment for the disease to thrive. Though pre ventive approaches such as good sanitation and distribution of insecticide treated nets (ITNs) (Curtis et al., 2006), have been employed as strategy towards the eradication of this disease, chemotherapy remains the most widely used approach. The ability of P. falciparum to develop resistance to effective and affordable drugs (Cheeseman et al., 2012; Jambou et al., 2005; Mller Hyde, 2010; Phyo et al., 2012) and to pyrethroids, the active principle of the insecticides treated nets (ITNs) (Fane et al., 2012; NGuessan et al., 2007) has made constant search for new pharmacotherapy imperative. Malaria parasite life cycle is a complex mechanism involving two hosts, human and female Anopheles mosquitoes. However, the clinical symptoms of the disease are associated with the invasion of the erythrocytes by the parasite, its growth, division inside the host cell and the cyclic cell lysis and reinvasion of new erythrocytes. The intra-erythrocytic survival and development of the parasite as well as the pathology of the infection are linked to structural and functional remodeling of the host cell through the export of parasite-encoded proteins (Botha et al., 2007; Miller et al., 2002; Pesce Blatch, 2009; Przyborski Lanzer, 2005). Meanwhile, attempts have been made to present an extensive description of the protein interaction network for P. falciparum (LaCount et al., 2005) and about 300 parasite-encoded proteins are predicted to be exported (Marti et al., 2004; Sargeant et al., 2006). Among the exported proteins are the molecular chaperones of the heat shock protein family (Nya lwidhe Lingelbach, 2006). Molecular chaperone are a family of proteins that function to stabilize proteins, facilitate their translocation across intracellular membranes, their degradation, and ensure that proteins in a cell are properly folded and functional (Hartl Hayer-Hartl, 2002; Hartl, 1996). PFA0660w belongs to an extended family of Hsp40 proteins predicted to be transported by the parasite into the host cell (Hiller et al., 2004; Marti et al., 2005; Sargeant et al., 2006). It is a Type II Hsp40 protein, said to be homologous to human DnaJB4, a cytosolic type II Hsp40, known to interact with human Hsp70 to facilitate protein folding, transport and assembly (Botha et al., 2007). Recent studies have localized PFA0660w into structures in the infected erythrocyte, called the J-dots (Kulzer et al., 2010); said to be exported in complex with P. falciparum Hsp70-x (PfHsp70-x) into the J dots (Kulzer et al., 2012) and failure to obtain a viable PFA0660w-knocked-out parasite (Maier et al., 2008), suggests that it may be essential for the survival of the parasite in the infected erythrocytes and therefore a potential target for drug action. 1.2 Malaria Infection 1.2.1 Background information Malaria, though curable and preventable, remains a life-threatening disease that was noted in more than 4,000 years ago and has being responsible for millions of death. World Health Organization (WHO) listed malaria among the most important infectious diseases of the tropics and form part of the sixth millennium development goal (MDG 6) (WHO | MDG 6: combat HIV/AIDS, malaria and other diseases, 2012). The target 6C of MDG 6 is to bring malaria and other major diseases to a halt by 2015 and begin to reverse their incidences. Strategies advocated by WHO to combat malaria includes prevention with the use of long-lasting insecticides treated bed-nets (ITNs) and indoor residual spraying, and rapid treatment with effective anti-malarial medicines with special focus on pregnant women and young children. WHO Roll Back Malaria further recommends that to control Plasmodium falciparum malaria during pregnancy, in addition to individual protection with ITNs and prompt management of anaemia and m alaria using effective anti-malaria drugs, intermittent preventive treatment (IPTp) or chemoprophylaxis should be encouraged (WHO | Malaria in pregnancy, 2012). Though, the World Health Organization (WHO) 2011 Malaria reports (WHO | World Malaria Report 2011, 2012) estimated at least 655 000 deaths as a result of malaria infection, mostly in Africa and among children under the age of 5 years, the mortality burden may actually be larger than previously estimated, thus, the need for improved supports by the funding organization to be able to achieve the much needed malaria elimination and eradication (Murray et al., 2012). Malaria is caused by the transmission of parasites to humans by female Anopheles mosquitoes during a blood meal. Plasmodium falciparum is known to be responsible for high rate of mortality, especially among children in sub-Saharan Africa, mostly under age 5 years (Breman, 2001; Greenwood et al., 2008; Hay et al., 2004; Rowe et al., 2006; Snow et al., 2005). Apart from the fact that many of the countries that are mostly affected are located in the tropical region of the world, increasing level of poverty, with its attendant economic consequences, coupled with lack of or improper sanitation and reduced access to prompt medication are factors that are creating enabling environment for the disease to thrive. Though preventive approaches such as the use of insecticide treated bed nets, IPTp and chemoprophylaxis with good sanitation (Curtis et al., 2006; WHO | Malaria in pregnancy, 2012), have been employed as strategy towards the eradication of this disease, the use of chemotherapeutic drugs remains the most widely used approach (Butler et al., 2010; DAlessandro, 2009). However, the success of this strategy has been hampered by the resilient of the parasite in continually creating resistance to the available drugs. The ability of P. falciparum to develop resistance to effective and affordable drugs (Cheeseman et al., 2012; Jambou et al., 2005; Mller Hyde, 2010; Phyo et al., 2012) and to pyrethroids, the active principle of the insecticides treated nets (ITNs) (Fane et al., 2012; NGuessan et al., 2007), has made constant search for new pharmacotherapy imperative. However, notwithstanding the centrality of chemoprophylaxis and chemotherapy in efforts at combating the menace of malaria infe ction (DAlessandro, 2009), and wide distribution of insecticide-impregnated bed nets, efforts aimed at enhancing long lasting protective immunity through vaccination, of which RTS,S is emerging as most promising vaccine formulation, have also been intensified (Ballou, 2009; Casares et al., 2010). 1.2.2 Life Cycle of Plasmodium falciparum Malaria parasite life cycle (Figure 1.1) is a complex mechanism involving two hosts, human and female Anopheles mosquitoes. The survival of the parasite during several stages of its development depends on its ability to invade and grow within multiple cell types and to evade host immune responses by using their specialized proteins (Florens et al., 2002; Greenwood et al., 2008). Sporozoites (infective stage), merozoites (erythrocytes invading stage), trophozoites (multiplying form in erythrocytes), and gametocytes (sexual stages) are stages involved in the development of the parasite. These stages are unique in shapes, structures and complementary proteins. The continuous changes in surface proteins and metabolic pathways during these stages help the parasites to survive the host immune response and create challenges for drugs and vaccines development (Florens et al., 2002). The sporogony or sexual phase occurs in mosquitoes, resulting in the development of numerous infective forms of the parasites which when ingested by human host induced disease. During a blood meal by female Anopheles mosquitoes from an individual infected with malaria, the male and female gametocytes of the parasite enter into the gut of the mosquito, adjust itself to the insect host environment and initiate the sporogonic cycle. The fusion of male and female gametes produced zygotes, which subsequently develop into actively moving ookinetes that pierced into the mosquito midgut wall to develop into oocysts. Each oocyst divides to produce numerous active haploid forms called sporozoites which are subsequently released into the mosquitos body cavity following the burst of the oocyst. The released sporozoites travel to and invade the mosquito salivary glands, from where they get injected into the human bloodstream during another blood meal, causing malaria infection (Barillas-Mury Kum ar, 2005; Ferguson Read, 2004; Hill, 2006). The parasite life cycle traverse two hosts (Man and Mosquito) with each stage involving complex cellular and molecular modifications. To prevent blood clots, Sporozoites infected saliva are deposited into Man during blood meal by female Anopheles mosquitoes, make their way to the liver, develop over time into hypnozoites (dormant stage, usually responsible for relapse of infection) or merozoites (that are released into blood stream to invade erythrocytes). The clinical symptoms of the disease are associated with the invasion of the erythrocytes by the parasite, its growth, division inside the host cell and the cyclic cell lysis and reinvasion of new erythrocytes. The schizogony or asexual phase of the life cycle occurs in human host. The cycle is initiated from the liver by the ingested sporozoites and later continues within the red blood cells, resulting in the clinical manifestations of the malaria disease. Following the introduction of invasive sporozoites into the skin after mosquito bite, they are either destroyed by macrophages, enter the lymphatics and drain into the lymph nodes from where they can develop into exoerythrocytic stages (Vaughan et al., 2008) and prime the T cells as a way of mounting protective immune response (Good Doolan, 2007) and/or blood vessel (Silvie et al., 2008b; Vaughan et al., 2008; Yamauchi et al., 2007), from where they made their way into the liver. While in the liver, sporozoites negotiate through the liver sinusoids, entered into hepatocytes, followed by multiplication and growth in parasitophorous vacuoles into schizonts, each of which contains thousands of merozoites, especially with P. falciparum (Ami no et al., 2006; Jones Good, 2006; Kebaier et al., 2009). Thrombospondin-related anonymous protein (TRAP) family and an actinmyosin motor has been show to help sporozoites in its continuous sequence of stick-and-slip motility (Baum et al., 2006; Mnter et al., 2009; Yamauchi et al., 2007) and that it growth and development within the liver cells is facilitated by the circumsporozoite protein of the parasite (Prudncio et al., 2006; Singh et al., 2007). This stick and slip motility prevent the parasite from been washed away by the circulating blood into kidney from where they can be destroyed and removed from the body. Motility is driven by an actin-myosin motor located underneath the plasma membrane. The sporozoite journey is propelled by a unique actin-myosin system, which allows extracellular migration, cell traversal and cell invasion (Kappe et al., 2004).This is a single cycle phase with no clinical symptoms, unlike the erythrocytic stage, which occurs repeatedly and characterize d with clinical manifestation. The hepatocytic merozoites are stored in vesicles called merosomes where they are protected from the phagocytotic action of Kupffer cells. The release of these merozoites into the blood stream via the lung capillaries initiates the blood stage of the infection (Silvie et al., 2008b). In some cases (as it can be found with P. vivax and P. ovale malaria) dormant sporozoites, called hypnozoites, are formed and remain in the liver for a long time. These hypnozoites are usually responsible for the development of relapse of clinical malaria infection and has been reported to be genotypically different from the infective sporozoites ingested after a mosquito bite (Cogswell, 1992; Collins, 2007). The development of the parasite within the red blood cells occur with precise cyclic accuracy with each repeated cycles producing hundreds of daughter cells that subsequently invades more red blood cells. The clinical symptoms of the disease are associated with the invasion of the erythrocytes by th e parasite, its growth, division inside the host cell and the cyclic cell lysis and reinvasion of new erythrocytes. The invasion of RBCs by the merozoites takes place within seconds and made possible by series of receptorligand interactions. The ability of the merozoites to quickly disappear from circulation into the RBCs protect its surface antigens from exposure to the host immune response (Cowman Crabb, 2006; Greenwood et al., 2008; Silvie et al., 2008b). Unlike P. Vivax, which invade the RBCs by binding to Duffy blood group, the more virulent P. falciparum possess varieties of Duffy binding-like (DBL) homologous proteins and the reticulocyte binding-like homologous proteins that allows it to recognize and bind effectively to different RBC receptors (Mayer et al., 2009; Weatherall et al., 2002). Micronemes, rhoptries, and dense granules are the specialized apical secretory organelles of the merozoite that help the merozoites to attach, invade, and establish itself in the red cel l. The successful formation of stable parasitehost cell junction is followed by entering into the cells through the erythrocyte bilayer. This entrance is made possible with the aid of the actinmyosin motor, proteins of the thrombospondin-related anonymous protein family (TRAP) and aldolase, leading to the creation of a parasitophorous vacuole, that isolate the intracellular ring parasite from the host-cell cytoplasm, thereby creating a conducive environment for its development (Bosch et al., 2007; Cowman Crabb, 2006; Haldar Mohandas, 2007). The intra-erythrocytic parasite is faced with the challenge of surviving in an environment devoid of standard biosynthetic pathways and intracellular organelles in the red cells. This challenge is overcome by the ability of the parasite to adjust its nutritional requirement to haemoglobin only, formation of a tubovesicular network, thereby expanding it surface area and by export of a range of remodeling and virulence factors into the red cell (Silvie et al., 2008b). Following the ingestion of the hemoglobin into the food vacuole, it is degraded to make available the amino acids for protein biosynthesis. Heme is a toxic free radical capable of destroying the parasite within the red blood cells. Heme polymerase is used by the parasite for the detoxification of heme and the resulting hemozoin is sequestrated as hemozoin. As the parasite grows and multiplies, new permeation pathways are created in the host cell membrane to help in the uptake of solutes from the extracellular medium, disp osal of metabolic wastes, and in initiating and sustaining electrochemical ion gradients, thereby preserving the osmotic stability of the infected red cells and thus, premature hemolysis (Kirk, 2001; Lew et al., 2003). 1.2.3 Control of Malaria infection Preventive measures are a critical step towards the control and eradication of malaria. Preventive approach can broadly be divided into two Infection control and Vector control. Infection control focuses on preventing the development of the disease as a result of occasional mosquito bite or relapse of previous infection (Lell et al., 2000; Walsh et al., 1999b). This involves the use of chemoprophylaxis. Travellers to malaria endemic countries are expected to start prophylaxis at least two weeks before and to continue up to two weeks after. One important target group in the infection control using chemoprophylaxis are the pregnant women. Intermittent preventive treatment for pregnant women (IPTp) is the globally acknowledge approach for prevention of malaria in pregnancy (Vallely et al., 2007; WHO | Malaria in pregnancy, 2012). Sulphadoxin-pyrimethamine (SP) has been used for this purpose and there are compelling arguments for the use of artesunate-SP (Jansen, 2011). To ensure long lasting prevention, this approach should be combined with vector control. Vector control focuses on protecting against mosquitoes bite, thereby preventing the transmission of the parasite to Man. Strategies for vector control include the use of residual spraying of insecticides, insect repellent cream or spray, sleeping under bed nets, especially, the insecticide impregnated bed nets (ITNs) and proper sanitation (Curtis et al., 2006; Lavialle-Defaix et al., 2011; WHO | Insecticide-treated materials,). WHO provides guideline for the production, preparation, distribution and the use of the ITNs (WHO | Insecticide-treated materials,). With the reported resistance to pyrathroids, an active principle of the insecticides treated bed nets (Fane et al., 2012; NGuessan et al., 2007), all strategies involving the use of chemical agents, also faces the global challenge of developing resistance. Training in proper sanitation and its sustainability from generation to generation is most probably the best approach in controlling the malaria disease. Personal and general hygiene which involve in-door and out-door cleaning, good refuse disposal practices, eradication of stagnant water, proper sewage disposal and clean, dry and uninterrupted drainages are examples of good sanitation practices that will not only prevent malaria infection, but also other killer diseases of the tropics. Sanitation is not only cheap and affordable; it is within the reach of everybody. 1.2.3.2 Malaria Chemotherapy Despite the use of preventive approaches outlined above (Curtis et al., 2006; WHO | Malaria in pregnancy, 2012), as strategy towards the eradication of this malaria, the use of chemotherapeutic drugs remains the most widely used approach (Butler et al., 2010; DAlessandro, 2009). They are widely employed as prophylaxis, suppressive and curative. However, the success of this strategy has been hampered by the resilient of the parasite in continually creating resistance to the available drugs. The ability of P. falciparum to develop resistance to effective and affordable drugs (Cheeseman et al., 2012; Jambou et al., 2005; Mller Hyde, 2010; Phyo et al., 2012) and to pyrethroids, the active principle of the insecticides treated nets (ITNs) (Fane et al., 2012; NGuessan et al., 2007), has made constant search for new pharmacotherapy imperative. Various approaches have been employed to identify new antimalaria agents with a view to reducing cost, ensuring availability and reducing the incidences of resistance (Rosenthal, 2003). Chemical modification of the existing antimalarial is a simple approach and required no extensive knowledge of the mechanism of drug action and the biology of the infection. Many drugs in use today have been produced using this approach, including chloroquine, primaquine and mefloquine from quinine (Stocks et al., 2001), 8-aminoquinoline, tafenoquine, from primaquine (Walsh et al., 1999a) and lumefantrine from halofantrine (van Vugt et al., 2000). Another approach is the use of plant derived compound with little or no chemical modification has led to the discovery of potent antimalarial such as artemisinins (Meshnick, 2001). Also, the use of other agents not originally designed for malaria such as folate antagonists, tetracyclines and antibiotics that were reported to be active against malaria parasit es (Clough Wilson, 2001) is another viable approach to drug discovery. Resistance reversals such verapamil, desipramine and trifluoperazine (van Schalkwyk et al., 2001) have also been used in combination with antimalaria drugs to improve therapy. Optimization of therapy with existing antimalaria agents is widely used as a productive approach towards improving therapy. Optimization of therapy underscore the need for combination therapy with newer and older drugs and with agents that are not original designed as antimalaria but which can potentiate the antimalaria property and/or block resistance to antimalaria agents. Thus for the combination to be ideal, it should improve antimalarial efficacy, providing additive or synergistic antiparasitic activity and slow the progression of parasite resistance to the antimalaria agents. For example, combination of artesunate with sulfadoxine/pyrimethamine (von Seidlein et al., 2000) or with amodiaquine (Adjuik et al., 2002), if devoid of underlying resistance to the artesunate partners which can lead to high rates recrudescence (Dorsey et al., 2002), may prove to be optimal antimalarial agents. Other combinations that have been effectively used include artesunate and mefloquine (Price et al., 1997) and artemether and lumefantrine (Lefevre et al., 2001). The combination of analog of proguanil (chlorproguanil) with dihydropteroate synthase (DHPS) inhibitor (dapsone), originally produced to treat leprosy (Mutabingwa et al., 2001) has open up a new and effective approach in antimalaria drug therapy. The use of dapsone and other drug resistance reversers such as verapamil, desipramine, trifluoperazine (van Schalkwyk et al., 2001) and Chlorpheniramine (Sowunmi et al., 1997) has shown potential for reducing the rate of drug resistance. Table 1.1: Classes and Mechanism of Antimalarial drugs CLASSES OF DRUGS Gametocidal Tafenoquine Gamatocidal Gametocidal biguanides (proguanil, cycloguanil), Trimethoprim CLASSES OF DRUGS Clindamycin, Spiramycin m ubiquinol to cytochrome C (Vaidya, 2001). Meanwhile, one important and innovative approach towards drug discovery in malaria chemotherapy is the search for new antimalaria drug target. Such targets include parasite membrane (Vial Calas, 2001), food vacuole (Banerjee et al., 2002), mitochondrial and apicoplast (Ralph et al., 2001; Vaidya, 2001). The cytosol, which is the centre of metabolic activities (e.g. folate metabolism and glycolysis) and enzymes activities have proven to be valuable as potential target for drug action (Plowe, 2001; Razakantoanina et al., 2000). To survive and develop within the erythrocytes, Plasmodium falciparum export most of its virulent factors into the cytosol of the infected erythrocytes. Among these are the molecular chaperones of the heat shock proteins which are focus of many researches and are increasingly gaining ground as potential target of drug action (Behr et al., 1992; Kumar et al., 1990). 1.2.3.3 Malaria Vaccines Notwithstanding the centrality of chemoprophylaxis and chemotherapy in efforts at combating the menace of malaria infection (DAlessandro, 2009), and wide distribution of insecticide-impregnated bed nets, efforts aimed at enhancing long lasting protective immunity through vaccination, of which RTS,S is emerging as most promising vaccine formulation, has been intensified (Ballou, 2009; Casares et al., 2010). These attempts at producing an effective vaccine against malaria infection has, however, for many years proved unsuccessful (Andr, 2003; Artavanis-Tsakonas et al., 2003). Having a vaccine that can completely block transmission from human to mosquito host can be a major limp towards global eradication of malaria. But, the absences of such immunity may explain the possible partnership between the parasite and the host, developed over a long time of co-habitation (Evans Wellems, 2002). On the other hand, a vaccine developed in line with the model of naturally acquired immunity that o ffers protections against morbidity and mortality, offers more encouragement. Such a vaccine will be a major step in the right direction and may not require regular booster vaccination like it would with vaccine that target infection transmission blockage (Struik Riley, 2004). Meanwhile, the development of natural immunity, after a long term exposure to the infection, especially with people living in the endemic areas has been reported (Baird, 1995; Hoffman et al., 1987; Rogier et al., 1996). The rate of acquired immunity in infants is faster than older children, but they also stand the chance of higher risk of developing severe malaria infection and anaemia (Aponte et al., 2007). Though, adults who, having obtained naturally acquired immunity, migrated to malaria-free zones, stands the risk of contacting the diseases upon return to their endemic region, documentary evidences however revealed that their responses to such re-infection are very rapid and tend to respond to treatment and recover faster than those who have not been previously xposed. (Di Perri G et al., 1994; Jelinek et al., 2002; Lepers et al., 1988). While this naturally acquired immunity is beneficial, it leaves the most vulnerable population (children and pregnant women though the mother may be immune, the foetus is not) at risk, as they are yet to gain enough exposure for such immunity to take place. Aponte et al., (2007) also showed that a reduced exposure toP. falciparumantigens through chemoprophylaxis early in life have the potential to delay immunity acquisition. Furthermore, it does not appear that naturally acquired immunity have any effect on transmission of malaria. This further explained the possibility of an evolving host-parasite relationship (Evans Wellems, 2002), which might have been developed over a long time host-parasite co-evolution. Therefore, understanding the compromises that may have developed over time between the parasite and the host may be an important approach towards developing a much needed vaccine. 1.3 Molecular and Cellular Basis of Malaria Infection Following blood meal by an Anopheles female mosquito accompany with the release of saliva to prevent blood coagulation (Beier, 1998), malaria parasites are deposited or ejection of into the skin (Frischknecht et al., 2004; Vanderberg Frevert, 2004). By continuous gliding in the skin, the sporozoite reach a blood vessel, breach the endothelial barrier and enter the blood circulation (Amino et al., 2007; Vanderberg Frevert, 2004) and/or breach a lymphatic vessel to enter the draining lymph node, where exoerythrocytic stages of sporozoites development may take place (Amino et al., 2006). A micronemal protein, called thrombospondin-related anonymous protein (TRAP), has been shown to be responsible for the gliding motility and invasion mosquito vector salivary gland and in mammalian host (Kappe et al., 1999). The sporozoite transversal to the liver and the merozoites invasion and remodeling of the host cells are complex but necessary processes for the survival and development of the par asite. 1.3.1 Cell Transversal Sporozoite possesses the ability to transverse cells i.e move in and out of the host cells by membrane disruption (Mota et al., 2002, 2001; Vanderberg Stewart, 1990). Among the proteins secreted by the micronemes that have been implicated in host cell traversal are SPECT1 (sporozoite microneme proteinessential forcelltraversal 1) and SPECT2 (Ishino et al., 2005, 2004). The absence of SPECT1orSPECT2in mutant sporozoite does not prevent gliding motility but prevent migration through host cells (Ishino et al., 2004).Other proteins of importance to sporozoite cell traversal prior to hepatocyte infection, includes TRAP-Like Protein (Moreira et al., 2008), a sporozoite secreted phospholipase (Bhanot et al., 2005), and celltraversal protein forookinete andsporozoite (Kariu et al., 2006). Similarly, the circumsporozoite protein (CSP) probably plays a role in targeting sporozoites to hepatocytes by interacting with heparin sulfate proteoglycans (Sinnis Sim, 1997). 1.3.2 Liver stage development Upon entering the bloodstream, infectious sporozoite makes it way to the liver. Circumsporozoite protein (CSP) is highly expressed at this stage of the parasite life cycle. Using the sporozoites that expresses fluorescent proteins under the control of CSP and intravital imaging, Frevert and colleagues were able to show the movement of sporozoites in the liver (Frevert et al., 2005). The study showed that sporozoite migrates through several hepatocytes before finally settling in one, form PV and begin the liver stage development. CSP, mediated by low-density lipoprotein receptor-related protein LRP-1, and other highly expressed proteins by Kupffer cells, play an important role in inhibiting the generation of reactive oxygen species via the generation of cyclic AMP (cAMP) which stimulates adenyl cyclase activity (Usynin et al., 2007). Ishino and co-workers reported that two parasite molecules P36 and P52/P36p are involved in sporozoite invasion of hepatocytes with the formation of a PV membrane (PVM) (Ishino et al., 2005). Apart from CSP, other gene product that has been implicated in liver stage development of the parasite includes sporozoite low complexity asparagine-rich protein (SAP1) (Aly et al., 2008) and sporozoite and liver stage asparagine-rich protein (SLARP) (Silvie et al., 2008a) 1.3.3 Erythrocyte Invasion Erythrocyte invasion involves four steps, namely, initial merozoites binding, reorientation and erythrocyte deformation, specific interaction and junction formation and parasite entry (Figure 1.2). Merozoite surface protein-1 (MSP-1) is a well characterized merozoite surface proteins implicated in initial merozoite binding. It has been reported to be uniformly distributed over the merozo

The Importance of Organ Donation Essay -- Organ Donor Health Medical P

The Importance of Organ Donation   Ã‚  Ã‚  Ã‚  Ã‚  Each day approximately 6,300 people die and what makes this haunting is that presently there are 83,513 people waiting for organs to be donated, yet each day 17 people die because they do not receive a transplant (http://www.donatelife.net/facts_stats.html). These statistics show that people who are waiting for organ transplants have a good chance at being saved and get what they need. The sad truth is though, because of the lack of people willing to donate organs, many people will continue to wait for organs to save their lives. ?Waiting lists of patients for organ transplants become longer as the need for transplantable organs increases? (Sheehy 1). Think back to how someone might feel when a close family member or friend dies. With out argument, the feeling one experiences when going through a time like that is one of the most painful experiences. The feeling when one gets when they know that they will never again see the person you loved so much, never hold th em, touch them, experience their presence. It is a horrible feeling. What many do not realize is simply by donating organs, you can help someone else not have to deal with that pain.   Ã‚  Ã‚  Ã‚  Ã‚  Organ donation is when someone who has died, has previously given permission for their organs to be taken from their body and transplanted into someone else?s who because of some sort of medical condition, can not survive off of their own. At the time of death one?s heart, intestine, kidneys, liver, lung, pancreas, pancreas islet cell, heart valves, bone, skin, corneas, veins, cartilage, and tendons can all be used for transplantation. Choosing to donate organs is beneficial to many people, morally the right thing to do when you pass on and, is also one of the most important ways for survival of many people.   Ã‚  Ã‚  Ã‚  Ã‚  Organ donation is often perceived with doubt because many people do not know the truth. There are many myths out about the donating of organs that cause many people to opt not to. What many do not realize is the truth about organ donation. The body of the donor after the surgery is not mangled up and is presentable for the funeral. Organ donation is ethical and should not be looked down upon. Organ donating is there to save lives, not to hurt anyone. Many people think that they should be paid or given something in return for donating their organs, which is... ...en through the example of Nickolas Green, when you donate organs you not only save one life, but often numerous. Your body has so many vital organs and tissues that can be donated and given to many different people. For many of these people, what you donate to them, can be a matter of life or death. If they don?t receive a donation soon enough, their time will run out and they will pass away. By donating organs you are giving of your body, something that will never again by seen after death. You are making the morally correct decision to help others. It seems we are all brought up to help others and give of yourself, and what better way to do so then by donating of your organs.   Ã‚  Ã‚  Ã‚  Ã‚  When you go to get your drivers licence, be sure to mark that you will donate. Put yourself in the shoes of someone waiting for a donation. They hear of people dying and yet nothing will happen for their benefit if these people don?t choose to donate. Picture you husband or wife, on their death bed unless someone will donate their organs. Make the right decision to bring happiness out of death. Do not put your organs to waste, help those in need, and choose to donate.   Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  

Human Cloning: Science or Madness? Essay -- Argumentative Persuasive T

Human Cloning: Science or Madness?      Ã‚  Ã‚   Despite evidence that nearly all cloned animals are plagued by significant genetic abnormalities, two scientist groups have announced their plans to impregnate women with cloned embryos, each proposing to create the world's first cloned human being.    Clones are created by injecting genetic material from a single cell of one person is into an egg cell that has had its genes removed. The cell is then stimulated to act like a fertilized egg and divide, becoming an embryo. Once the embryo reaches an appropriate stage it is then implanted into a woman's womb, and the resulting baby would be like an identical twin to the donor.    Since the cloning of the sheep named Dolly in 1997, scientists have been working hard to create cloned human embryos for research and reproduction. During a hearing on human cloning, Panayiotis Zavos, a Kentucky based reproductive expert, told scientists, "The research must go on." Zavos is working with Italian fertility specialist Severino Antinori, who gained headline news in 1994 when he enabled a 62-year old woman to have a baby. Along with the Zavos and Antinori team are the scientists with Clonaid, an extraterrestrial Raelian movement based in Canada who claims cloning our bodies is the next step towards everlasting life.       Dr. Bridgette Boisselier is a Raelian Bishop and director of the human cloning project at Clonaid. The Raelian movement claims humanity was created by "space scientists," and "once we can clone exact replicas of ourselves, the next step will be to transfer our memory and personality into our newly cloned brains, which will allow us to truly live forever. Since we will be able to remember all our past, we wil... ...t proponents of human cloning claim this technology will help couples with infertility problems. Bragdon v. Abbot, 118 S.Ct. 2196 (1998), is cited as evidence that infertility is a disability and reproduction is a major life activity that is a fundamental human right. Human cloning advocates argue the development of a technology that can give an infertile and childless couple the right to reproduce, have a healthy biological child of their own, completing their biological "life cycle," is a constitutional right that should not be outlawed.    Works Cited: National Institutes of Health, NIH Update on Existing Human Embryonic Stem Cells, August 2001 The Associated Press, Votes Kill Efforts to Use Embryos for Research, August 2001 The White House: Office of the the Press Secretary, White House Fact Sheet Embryonic Stem Cell Research, August 2001   

Principles of Organizational Communication Essay

Two ladies wished to sit near one of the managers; the manager was unaware of this. As everyone took their seats at the tables, only one of the ladies was able to sit at the same table as the manager. The lady who was not able to sit on the manager’s table became quite upset and the following day at work refused to speak to the other girl. All the colleagues in the office who were aware of the situation did not pay too much attention to the dispute as they thought it would pass the next day, however as the week went on, the dispute continued and then other parties became involved in taking sides. What communication theories apply to these problems? It’s the leader’s job to point people in the right direction with clear, coherent, and consistent communication designed and planned thoughtfully and in advance. The leader of today thus has to lead with a clear direction in mind, and at the same time, ensure that the rest of the team understands which direction they are going. It is only when the whole entire team, together with the leader are working towards a common goal and final destination that success can really be achieved. Communication is thus essential because leaders must be able to communicate the goals and directions to the team other than being able to define it. Finally, they must communicate in such a way that the team will be inspired and motivated to take action. What organizational theories or perspectives are apparent? Principle; this is a narrower process of developing and maintaining procedures. This principle gives clear structure and rules which considers changing environment. It applies to the organization, powers, duties and its functions. In relationship to organizations today we do see that there is a rigid form of rules and power being installed by organizations such as the Unity of command. What information is missing? In week two the atmosphere became quite volatile and the work rate of the staff was definitely affected. In the case I encountered at work, I believed the conflict was just a clash of personalities between the two people concerned, however as the conflict evolved there became a deeper meaning to the reasons behind the problem, which moved onto to needs and expectations. What assumptions are we making about the organization, its people, and their problems? Lack of communication skills training. Lack of confidence in the quality, attitude, and management to the staff. Good idea to hire positive personalities that are good with people. This will help the company build a positive image for itself. Sensitivity Who or what appears to be most responsible for the communication problems? Good communication is the key to a successful business. Identifying the signs of communication problems is the first step in solving communication issues. Some of the things to look for are mistakes, apathy, lack of cooperation, frequent complaining, and poor communication can increase the issues. Diagnosing the problem and finding ways to lessen the impact can help reduce conflict and restore business productivity What are the shared realities in the organization? Empathy. The ability to understand the emotional makeup of other people. A skill in treating people according to their emotional reactions. Before make decision I think leader should think as the way employees think then they can make intelligent decisions Are the principal individuals good communicators? Everyone needs to take the time to listen and reflect on what is being said, good communication requires everyone to participate fully. Knowledge of a culture is key to business success and to recognize differences sometimes requires you to put aside your own sensitivities to do what is necessary to work together. Are the principals in this case assuming responsibilities for the communication behaviors? No. Both the manager and the employee have the responsibility of seeking clarification whether they understand each other to minimize conflicts between them. Skills What skills do the case principals exhibit? Analytical problem solving skills. Make decisions based on well reasoned assumptions. Alert to personal characteristics and relationships among the principals of the case. What additional skills are needed? Understanding the situation in which the problem is located. Sort out the relevant from the irrelevant, facts from the assumptions and goals from actions, and organize the issues into a clear exposition of the problems at hand. How could these skills be developed? Through understanding SWOT (strengths weaknesses, opportunities and threats) analysis. It helps to convert wish statements into concrete attainable objectives. What overall organizational skills are lacking? The skill of making logical consistencies with the situation analysis that was done. What are the major organizational strengths? Qualitative and quantitative analytical skills, including problem identification skills, data handling skills and critical thinking skills. Application skills, using various tools, techniques and theories. Oral communication skills, including speaking, listening and debating skills. Values What is important or valuable to the involved individuals? Being able to understand and deal with the different viewpoints and perspectives of the other employees on their team Do they share similar values? No. Some need to display ‘aggressive hospitality,’ that is, be encouraged to provide good customer service to other employees well beyond their expectations. How would you describe the culture of the organization? Good communication flow, its diversity and various languages. Having people with different background and skills is one of the most important benefits for one organization. Are the individual and organizational goals compatible? Yes. Everyone is working together and is ready to give and take, help and support one another because the main focus is to accomplish their mission. All the team members have a common goal to achieve. Develop alternatives and test the â€Å"reality† of possible solutions What should be done? Everyone needs to have a brainstorm session to find a solution for the problem, that way there is high probability of obtaining many different and creative ideas. This effort enables the team to obtain many alternatives and implement the best action plan and assign the tasks to the people involved. How many alternatives can be generated? 5. They can use Maslow’s Hierarchy of human needs and it can be classified into five categories (physiological, security, belongingness, esteem and self-actualization).